Standard Name	SNC1 1
Systematic Name	YAL030W
Feature Type	ORF, Verified
Description	Vesicle membrane receptor protein (v-SNARE); involved in the fusion between Golgi-derived secretory vesicles with the plasma membrane; proposed to be involved in endocytosis; member of the synaptobrevin/VAMP family of R-type v-SNARE proteins; SNC1 has a paralog, SNC2, that arose from the whole genome duplication (2, 3, 4, 5)
Name Description	Suppressor of the Null allele of CAP 1

Chromosomal Location	ChrI:87286 to 87752 | ORF Map | GBrowse

	View Computational GO annotations for SNC1
Molecular Function
Manually curated	SNAP receptor activity (IDA)
Biological Process
Manually curated	endocytosis (IMP) exocytosis (IMP) Golgi to plasma membrane transport (IMP) vesicle fusion (IDA)
Cellular Component
Manually curated	cellular bud neck (IDA) endosome (IDA) plasma membrane (IDA) SNARE complex (IDA) trans-Golgi network (IDA) transport vesicle membrane (IDA)

Classical genetics
overexpression	actin cytoskeleton morphology: abnormal budding index: abnormal cell cycle progression in G2 phase: abnormal cell size: increased nuclear morphology: abnormal
Large-scale survey
null	proton accumulation: decreased competitive fitness: increased resistance to streptomycin: decreased resistance to cycloheximide: decreased viable
overexpression	filamentous growth: decreased resistance to sirolimus: decreased vegetative growth: decreased
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	108 total interaction(s) for 56 unique genes/features.
Physical Interactions	Affinity Capture-MS: 3 Affinity Capture-RNA: 4 Affinity Capture-Western: 33 Co-crystal Structure: 2 PCA: 1 Reconstituted Complex: 3 Two-hybrid: 5
Genetic Interactions	Dosage Growth Defect: 7 Dosage Rescue: 13 Negative Genetic: 12 Phenotypic Enhancement: 4 Synthetic Growth Defect: 5 Synthetic Lethality: 12 Synthetic Rescue: 4
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrI:87286 to 87752 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..102 87286..87387 2011-02-03 1996-07-31 Intron 103..215 87388..87500 2011-02-03 1996-07-31 CDS 216..467 87501..87752 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS) Intron (103 - 215)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000000028