SLX1/YBR228W Summary Help

SLX1 BASIC INFORMATION

Standard Name SLX1
Systematic Name YBR228W
Feature Type ORF, Verified
Description Subunit of a complex, with Slx4p, that hydrolyzes 5' branches from duplex DNA in response to stalled or converging replication forks; function overlaps with that of Sgs1p-Top3p (1)
Name Description Synthetic Lethal of unknown (X) function 2
GO Annotations All SLX1 GO evidence and references
    View Computational GO annotations for SLX1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All SLX1 Phenotype details and references
Classical genetics
null
Large-scale survey
null
Interactions SLX1 All interactions details and references
  View additional details at BioGRID
65 total interaction(s) for 39 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 2
  • Affinity Capture-Western: 3
  • Co-purification: 1
  • Two-hybrid: 3
Genetic Interactions
  • Negative Genetic: 40
  • Phenotypic Enhancement: 2
  • Positive Genetic: 1
  • Synthetic Growth Defect: 4
  • Synthetic Lethality: 9
Sequence Information
ChrII:675308 to 676222 | ORF Map | GBrowse
Gbrowse
Last Update Coordinates: 2004-07-16 | Sequence: 1997-01-28
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..915 675308..676222 2004-07-16 1997-01-28
Post-translational Modifications PhosphoGRID | PhosphoPep Database
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000000432

SLX1 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
 GBrowse
  • Literature
  • Retrieve Sequences
  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
  • Maps & Displays
  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for SLX1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for SLX1]

1) Fricke WM and Brill SJ  (2003) Slx1-Slx4 is a second structure-specific endonuclease functionally redundant with Sgs1-Top3. Genes Dev 17(14):1768-78
2) Mullen JR, et al.  (2001) Requirement for three novel protein complexes in the absence of the Sgs1 DNA helicase in Saccharomyces cerevisiae. Genetics 157(1):103-18