SLI1/YGR212W Summary Help

Standard Name SLI1 1
Systematic Name YGR212W
Feature Type ORF, Verified
Description N-acetyltransferase; confers resistance to the sphingolipid biosynthesis inhibitor myriocin (ISP-1) by converting it into N-acetyl-myriocin, co-operates with Ypk1p in mediating resistance to myriocin (1)
Name Description Sphingosine-Like Immunosuppressant resistant gene 1
Chromosomal Location
ChrVII:917040 to 918446 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All SLI1 GO evidence and references
  View Computational GO annotations for SLI1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 5 genes
Resources
Large-scale survey
null
overexpression
Resources
5 total interaction(s) for 4 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1
  • Co-purification: 1

Genetic Interactions
  • Dosage Rescue: 1
  • Phenotypic Suppression: 1
  • Positive Genetic: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 468
Molecular Weight (Da) 54,473
Isoelectric Point (pI) 6.71
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrVII:917040 to 918446 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1407 917040..918446 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000003444
References cited on this page View Complete Literature Guide for SLI1
1) Momoi M, et al.  (2004) SLI1 (YGR212W) is a major gene conferring resistance to the sphingolipid biosynthesis inhibitor ISP-1, and encodes an ISP-1 N-acetyltransferase in yeast. Biochem J 381(Pt 1):321-8