SIP3/YNL257C Summary Help

Standard Name SIP3 1, 2
Systematic Name YNL257C
Feature Type ORF, Verified
Description Transcription cofactor; acts through interaction with DNA-bound Snf1p; C-terminal region has a putative leucine zipper motif; potential Cdc28p substrate; SIP3 has a paralog, YSP1, that arose from the whole genome duplication (2, 3, 4)
Name Description SNF1-Interacting Protein 1
Chromosomal Location
ChrXIV:164320 to 160631 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All SIP3 GO evidence and references
  View Computational GO annotations for SIP3
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Targets 11 genes
Regulators 4 genes
Resources
Classical genetics
null
Large-scale survey
null
Resources
56 total interaction(s) for 54 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 5
  • Biochemical Activity: 1
  • Two-hybrid: 2

Genetic Interactions
  • Negative Genetic: 46
  • Phenotypic Enhancement: 1
  • Synthetic Growth Defect: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 1,229
Molecular Weight (Da) 142,818
Isoelectric Point (pI) 8.98
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXIV:164320 to 160631 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..3690 164320..160631 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005201
References cited on this page View Complete Literature Guide for SIP3
1) Yang X, et al.  (1992) A protein kinase substrate identified by the two-hybrid system. Science 257(5070):680-2
2) Lesage P, et al.  (1994) Analysis of the SIP3 protein identified in a two-hybrid screen for interaction with the SNF1 protein kinase. Nucleic Acids Res 22(4):597-603
3) Ubersax JA, et al.  (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64
4) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61