SHE10/YGL228W Summary Help

Standard Name SHE10 1
Systematic Name YGL228W
Feature Type ORF, Verified
Description Protein involved in outer spore wall assembly; likely involved directly in dityrosine layer assembly; putative GPI-anchored protein; overexpression causes growth arrest; SHE10 has a paralog, OSW7/YFR039C, that arose from the whole genome duplication and deletion of both SHE10 and OWS7 results in reduced dityrosine fluorescence from the spore wall relative to other mutants (1, 2, 3, 4)
Name Description Sensitivity to High Expression 1
Chromosomal Location
ChrVII:67598 to 69331 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All SHE10 GO evidence and references
  View Computational GO annotations for SHE10
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 11 genes
Resources
Classical genetics
overexpression
Large-scale survey
null
overexpression
Resources
40 total interaction(s) for 35 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 2
  • Affinity Capture-RNA: 2

Genetic Interactions
  • Dosage Growth Defect: 1
  • Negative Genetic: 29
  • Phenotypic Suppression: 1
  • Positive Genetic: 3
  • Synthetic Growth Defect: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 577
Molecular Weight (Da) 66,862
Isoelectric Point (pI) 5.7
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrVII:67598 to 69331 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2004-07-15 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1734 67598..69331 2004-07-15 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000003197
References cited on this page View Complete Literature Guide for SHE10
1) Espinet C, et al.  (1995) An efficient method to isolate yeast genes causing overexpression-mediated growth arrest. Yeast 11(1):25-32
2) De Groot PW, et al.  (2003) Genome-wide identification of fungal GPI proteins. Yeast 20(9):781-96
3) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
4) Lin CP, et al.  (2013) A Highly Redundant Gene Network Controls Assembly of the Outer Spore Wall in S. cerevisiae. PLoS Genet 9(8):e1003700