Standard Name	SGN1 1 (see Nomenclature conflict Note)
Systematic Name	YIR001C
Alias	RBP1 , RBP29
Feature Type	ORF, Verified
Description	Cytoplasmic RNA-binding protein, contains an RNA recognition motif (RRM); may have a role in mRNA translation, as suggested by genetic interactions with genes encoding proteins involved in translational initiation (2)
Name Description	Slower Growth on Non-fermentable carbon sources 1

Chromosomal Location	ChrIX:356895 to 356143 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.

	View Computational GO annotations for SGN1
Molecular Function
Manually curated	poly(A) RNA binding (IDA)
Biological Process
Manually curated	mRNA metabolic process (IGI)
Cellular Component
Manually curated	cytoplasm (IDA)

Classical genetics
overexpression	resistance to nocodazole: decreased
Large-scale survey
null	anaerobic growth: decreased competitive fitness: decreased haploinsufficient resistance to hydroxyurea: increased resistance to cycloheximide: decreased resistance to amitrole: decreased resistance to fluconazole: decreased resistance to bleomycin: increased toxin resistance: decreased vacuolar morphology: abnormal viable
overexpression	cell cycle progression: abnormal resistance to sirolimus: decreased resistance to LY-83583: decreased vegetative growth: decreased
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	97 total interaction(s) for 68 unique genes/features.
Physical Interactions	Affinity Capture-MS: 33 Affinity Capture-RNA: 1 Affinity Capture-Western: 2 Biochemical Activity: 1 PCA: 3 Protein-peptide: 1 Two-hybrid: 3
Genetic Interactions	Dosage Growth Defect: 4 Dosage Rescue: 3 Negative Genetic: 38 Positive Genetic: 4 Synthetic Growth Defect: 4
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrIX:356895 to 356143 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
Last Update	Coordinates: 2011-02-03 | Sequence: 1994-12-10
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..753 356895..356143 2011-02-03 1994-12-10
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000001440