SFK1/YKL051W Summary Help

Standard Name SFK1 1
Systematic Name YKL051W
Feature Type ORF, Verified
Description Plasma membrane protein that may act to generate normal levels of PI4P; may act together with or upstream of Stt4p; at least partially mediates proper localization of Stt4p to the plasma membrane (1)
Name Description Suppressor of Four Kinase 1
Chromosomal Location
ChrXI:341312 to 342373 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All SFK1 GO evidence and references
  View Computational GO annotations for SFK1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 10 genes
Resources
Large-scale survey
null
overexpression
Resources
66 total interaction(s) for 62 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 2
  • Affinity Capture-RNA: 2
  • Affinity Capture-Western: 2
  • Biochemical Activity: 2
  • PCA: 45

Genetic Interactions
  • Dosage Rescue: 1
  • Negative Genetic: 7
  • Phenotypic Enhancement: 1
  • Positive Genetic: 2
  • Synthetic Lethality: 1
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 353
Molecular Weight (Da) 40,462
Isoelectric Point (pI) 7.28
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXI:341312 to 342373 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1062 341312..342373 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001534
References cited on this page View Complete Literature Guide for SFK1
1) Audhya A and Emr SD  (2002) Stt4 PI 4-kinase localizes to the plasma membrane and functions in the Pkc1-mediated MAP kinase cascade. Dev Cell 2(5):593-605