SFC1/YJR095W Summary Help

Standard Name SFC1 1
Systematic Name YJR095W
Alias ACR1
Feature Type ORF, Verified
Description Mitochondrial succinate-fumarate transporter; transports succinate into and fumarate out of the mitochondrion; required for ethanol and acetate utilization (2, 3)
Name Description Succinate-Fumarate Carrier 1
Chromosomal Location
ChrX:609773 to 610741 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All SFC1 GO evidence and references
  View Computational GO annotations for SFC1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 5 genes
Resources
Classical genetics
null
Large-scale survey
null
overexpression
Resources
33 total interaction(s) for 30 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 6
  • Affinity Capture-RNA: 1
  • Biochemical Activity: 2
  • PCA: 2

Genetic Interactions
  • Negative Genetic: 15
  • Phenotypic Suppression: 2
  • Positive Genetic: 4
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 322
Molecular Weight (Da) 35,340
Isoelectric Point (pI) 10.59
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrX:609773 to 610741 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..969 609773..610741 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | TCDB | UniProtKB
Primary SGDIDS000003856
References cited on this page View Complete Literature Guide for SFC1
1) Palmieri L, et al.  (2000) Identification and functions of new transporters in yeast mitochondria. Biochim Biophys Acta 1459(2-3):363-9
2) Fernandez M, et al.  (1994) ACR1, a gene encoding a protein related to mitochondrial carriers, is essential for acetyl-CoA synthetase activity in Saccharomyces cerevisiae. Mol Gen Genet 242(6):727-35
3) Palmieri L, et al.  (1997) Identification of the yeast ACR1 gene product as a succinate-fumarate transporter essential for growth on ethanol or acetate. FEBS Lett 417(1):114-8