SER33/YIL074C Summary Help

Standard Name SER33 1
Systematic Name YIL074C
Feature Type ORF, Verified
Description 3-phosphoglycerate dehydrogenase; catalyzes the first step in serine and glycine biosynthesis; SER33 has a paralog, SER3, that arose from the whole genome duplication (1, 2)
Name Description SERine requiring 1
Chromosomal Location
ChrIX:222490 to 221081 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All SER33 GO evidence and references
  View Computational GO annotations for SER33
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Regulators 10 genes
Resources
Pathways
Classical genetics
null
Large-scale survey
null
Resources
47 total interaction(s) for 30 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 9
  • Affinity Capture-Western: 1
  • Biochemical Activity: 4
  • Two-hybrid: 9

Genetic Interactions
  • Dosage Rescue: 1
  • Negative Genetic: 3
  • Phenotypic Enhancement: 1
  • Phenotypic Suppression: 10
  • Positive Genetic: 2
  • Synthetic Growth Defect: 4
  • Synthetic Lethality: 2
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 469
Molecular Weight (Da) 51,188
Isoelectric Point (pI) 6.39
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIX:222490 to 221081 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1994-12-10
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1410 222490..221081 2011-02-03 1994-12-10
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001336
References cited on this page View Complete Literature Guide for SER33
1) Albers E, et al.  (2003) Ser3p (Yer081wp) and Ser33p (Yil074cp) are phosphoglycerate dehydrogenases in Saccharomyces cerevisiae. J Biol Chem 278(12):10264-72
2) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61