SER3/YER081W Summary Help

Standard Name SER3 1
Systematic Name YER081W
Feature Type ORF, Verified
Description 3-phosphoglycerate dehydrogenase; catalyzes the first step in serine and glycine biosynthesis; SER3 has a paralog, SER33, that arose from the whole genome duplication (1, 2)
Name Description SERine requiring 1
Chromosomal Location
ChrV:322686 to 324095 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All SER3 GO evidence and references
  View Computational GO annotations for SER3
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Regulators 11 genes
Resources
Pathways
Large-scale survey
null
Resources
52 total interaction(s) for 36 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 13
  • Affinity Capture-RNA: 2
  • Affinity Capture-Western: 1
  • Two-hybrid: 18

Genetic Interactions
  • Dosage Rescue: 1
  • Negative Genetic: 7
  • Phenotypic Enhancement: 1
  • Positive Genetic: 3
  • Synthetic Growth Defect: 3
  • Synthetic Lethality: 2
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 469
Molecular Weight (Da) 51,193
Isoelectric Point (pI) 5.37
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrV:322686 to 324095 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1410 322686..324095 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000000883
References cited on this page View Complete Literature Guide for SER3
1) Albers E, et al.  (2003) Ser3p (Yer081wp) and Ser33p (Yil074cp) are phosphoglycerate dehydrogenases in Saccharomyces cerevisiae. J Biol Chem 278(12):10264-72
2) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61