SER1/YOR184W Summary Help

SER1 BASIC INFORMATION

Standard Name SER1 1, 2
Systematic Name YOR184W
Alias ADE9 3
Feature Type ORF, Verified
Description 3-phosphoserine aminotransferase, catalyzes the formation of phosphoserine from 3-phosphohydroxypyruvate, required for serine and glycine biosynthesis; regulated by the general control of amino acid biosynthesis mediated by Gcn4p (3, 4, 5)
Name Description SERine requiring 6
GO Annotations All SER1 GO evidence and references
    View Computational GO annotations for SER1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Pathways
Mutant Phenotype All SER1 Phenotype details and references
Classical genetics
null
Large-scale survey
null
Interactions SER1 All interactions details and references
39 total interaction(s) for 38 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 4
  • Affinity Capture-RNA: 1
  • Biochemical Activity: 3
  • Two-hybrid: 1
Genetic Interactions
  • Dosage Rescue: 1
  • Phenotypic Enhancement: 17
  • Phenotypic Suppression: 2
  • Synthetic Growth Defect: 2
  • Synthetic Lethality: 8
Sequence Information
ChrXV:679358 to 680545 | ORF Map | GBrowse
Gbrowse
Genetic position: 98.2 cM
Last Update Coordinates: 2006-01-05 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..1188 679358..680545 2006-01-05 1996-07-31
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000005710

SER1 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
 GBrowse
  • Literature
  • Retrieve Sequences
  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
  • Maps & Displays
  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for SER1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for SER1]

1) Johnston, J.R.  (1962) Studies in meiotic and mitotic recombination in Saccharomyces cerevisiae. Ph.D Thesis
2) Lowenstein, R.  (1973) Genetic studies in Saccharomyces cerevisiae. Ph.D Thesis
3) Buc PS and Rolfes RJ  (1999) ade9 is an allele of SER1 and plays an indirect role in purine biosynthesis. Yeast 15(13):1347-55
4) Melcher K and Entian KD  (1992) Genetic analysis of serine biosynthesis and glucose repression in yeast. Curr Genet 21(4-5):295-300
5) Melcher K, et al.  (1995) Molecular analysis of the yeast SER1 gene encoding 3-phosphoserine aminotransferase: regulation by general control and serine repression. Curr Genet 27(6):501-8
6) Ogur M, et al.  (1977) "Active" one-carbon generation in Saccharomyces cerevisiae. J Bacteriol 129(2):926-33