RPN2/YIL075C Summary Help

RPN2 BASIC INFORMATION

Standard Name RPN2 1
Systematic Name YIL075C
Alias SEN3 2
Feature Type ORF, Verified
Description Subunit of the 26S proteasome, substrate of the N-acetyltransferase Nat1p (2, 3)
Name Description Regulatory Particle Non-ATPase 1
GO Annotations All RPN2 GO evidence and references
    View Computational GO annotations for RPN2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All RPN2 Phenotype details and references
Classical genetics
conditional
Large-scale survey
null
Interactions RPN2 All interactions details and references
164 total interaction(s) for 73 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 95
  • Affinity Capture-Western: 9
  • Biochemical Activity: 5
  • Co-fractionation: 1
  • Co-purification: 4
  • PCA: 1
  • Reconstituted Complex: 8
  • Two-hybrid: 1
Genetic Interactions
  • Dosage Rescue: 1
  • Phenotypic Enhancement: 7
  • Phenotypic Suppression: 1
  • Synthetic Growth Defect: 26
  • Synthetic Lethality: 4
  • Synthetic Rescue: 1
Sequence Information
ChrIX:220697 to 217860 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Last Update Coordinates: 1994-12-10 | Sequence: 1994-12-10
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..2838 220697..217860 1994-12-10 1994-12-10
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000001337

RPN2 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
 GBrowse
  • Literature
  • Retrieve Sequences
  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
  • Maps & Displays
  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for RPN2

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for RPN2]

1) Finley D, et al.  (1998) Unified nomenclature for subunits of the Saccharomyces cerevisiae proteasome regulatory particle. Trends Biochem Sci 23(7):244-5
2) DeMarini DJ, et al.  (1995) The yeast SEN3 gene encodes a regulatory subunit of the 26S proteasome complex required for ubiquitin-dependent protein degradation in vivo. Mol Cell Biol 15(11):6311-21
3) Kimura Y, et al.  (2003) N-Terminal modifications of the 19S regulatory particle subunits of the yeast proteasome. Arch Biochem Biophys 409(2):341-8