SEG2/YKL105C Summary Help

Standard Name SEG2 1, 2
Systematic Name YKL105C
Feature Type ORF, Verified
Description Eisosome component; likely plays only minor role in eisosome assembly; shown to interact with Seg1p; similar to A. gossypii SEG gene which is important for stabilizing eisosomes; SEG2 has a paralog, SEG1, that arose from the whole genome duplication (2, 3, 4)
Name Description Stability of Eisosomes Guaranteed 1
Chromosomal Location
ChrXI:242583 to 239185 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All SEG2 GO evidence and references
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 4 genes
Resources
Large-scale survey
null
Resources
19 total interaction(s) for 15 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 5
  • Affinity Capture-RNA: 1
  • Co-purification: 1
  • Two-hybrid: 8

Genetic Interactions
  • Negative Genetic: 3
  • Synthetic Lethality: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 1,132
Molecular Weight (Da) 125,592
Isoelectric Point (pI) 5.58
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXI:242583 to 239185 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..3399 242583..239185 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001588
References cited on this page View Complete Literature Guide for SEG2
1) Seger S and Philippsen P  (2010) personal communication
2) Moreira KE, et al.  (2012) Seg1 controls eisosome assembly and shape. J Cell Biol 198(3):405-20
3) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
4) Seger S, et al.  (2011) Formation and stability of eisosomes in the filamentous fungus Ashbya gossypii. J Cell Sci 124(Pt 10):1629-34