SEE1/YIL064W Summary Help

Standard Name SEE1 1
Systematic Name YIL064W
Feature Type ORF, Verified
Description Probable lysine methyltransferase; involved in the dimethylation of eEF1A (Tef1p/Tef2p); sequence similarity to S-adenosylmethionine-dependent methyltransferases of the seven beta-strand family; role in vesicular transport (1, 2, 3, 4)
Name Description Secretion and Early Endocytosis 1
Chromosomal Location
ChrIX:241943 to 242716 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All SEE1 GO evidence and references
  View Computational GO annotations for SEE1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Regulators 1 genes
Resources
Classical genetics
null
Large-scale survey
null
Resources
21 total interaction(s) for 21 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 3
  • Biochemical Activity: 2

Genetic Interactions
  • Negative Genetic: 13
  • Synthetic Growth Defect: 2
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 257
Molecular Weight (Da) 28,689
Isoelectric Point (pI) 4.79
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIX:241943 to 242716 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1994-12-10
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..774 241943..242716 2011-02-03 1994-12-10
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001326
References cited on this page View Complete Literature Guide for SEE1
1) Martin-Granados C, et al.  (2008) Absence of See1p, a widely conserved Saccharomyces cerevisiae protein, confers both deficient heterologous protein production and endocytosis. Yeast 25(12):871-7
2) Katz JE, et al.  (2003) Automated identification of putative methyltransferases from genomic open reading frames. Mol Cell Proteomics 2(8):525-40
3) Lipson RS, et al.  (2010) Two novel methyltransferases acting upon eukaryotic elongation factor 1A in Saccharomyces cerevisiae. Arch Biochem Biophys 500(2):137-143
4) Couttas TA, et al.  (2012) Methylation of translation-associated proteins in Saccharomyces cerevisiae: Identification of methylated lysines and their methyltransferases. Proteomics 12(7):960-72