Standard Name	SED1 1
Systematic Name	YDR077W
Feature Type	ORF, Verified
Description	Major stress-induced structural GPI-cell wall glycoprotein; associates with translating ribosomes, possible role in mitochondrial genome maintenance; ORF contains two distinct variable minisatellites; SED1 has a paralog, SPI1, that arose from the whole genome duplication (2, 3, 4, 5, 6, 7)
Name Description	Suppression of Exponential Defect 1

Chromosomal Location	ChrIV:600793 to 601809 | ORF Map | GBrowse

	View Computational GO annotations for SED1
Molecular Function
Manually curated	structural constituent of cell wall (IMP)
Biological Process
Manually curated	fungal-type cell wall organization (IEP, IMP) mitochondrial genome maintenance (IMP)
Cellular Component
Manually curated	fungal-type cell wall (IDA, ISS) mitochondrion (IDA) ribosome (IDA)

Classical genetics
null	oxidative stress resistance: decreased resistance to nelfinavir: decreased resistance to enzymatic treatment: decreased respiratory growth: decreased rate toxin resistance: increased vegetative growth: decreased
Large-scale survey
null	competitive fitness: decreased resistance to (S)-lactic acid: increased vacuolar morphology: abnormal viable
overexpression	vegetative growth: decreased rate
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	37 total interaction(s) for 31 unique genes/features.
Physical Interactions	Affinity Capture-RNA: 5 Affinity Capture-Western: 2 PCA: 1 Two-hybrid: 6
Genetic Interactions	Dosage Rescue: 2 Negative Genetic: 10 Phenotypic Enhancement: 6 Synthetic Growth Defect: 2 Synthetic Lethality: 2 Synthetic Rescue: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrIV:600793 to 601809 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1017 600793..601809 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000002484