SCEI/Q0160 Summary

Standard Name	SCEI (see Nomenclature conflict Note)
Systematic Name	Q0160
Feature Type	ORF, Verified
Description	I-SceI DNA endonuclease, encoded by the mitochondrial group I intron of the 21S_rRNA gene; mediates gene conversion that propagates the intron into intron-less copies of the 21S_rRNA gene (1, 2, 3, 4) Also known as: OMEGA
Gene Product Alias	I-SceIV

Chromosomal Location	ChrMito:61022 to 61729 \| ORF Map \| GBrowse

	View Computational GO annotations for SCEI
Molecular Function
Manually curated	endonuclease activity (IDA)
Biological Process
Manually curated	intron homing (TAS)
Cellular Component
Manually curated	mitochondrion (TAS)

	1 total interaction(s) for 1 unique genes/features.
Physical Interactions	Biochemical Activity: 1
Resources	BioGRID \| BOND \| BioPIXIE \| CYC2008 (complexes) \| Complexome \| DRYGIN \| GeneMANIA \| InterologFinder

Expression Summary


Resources	Expression Summary \| Cell cycle and metabolic oscillation \| Cell cycle transcript profile \| Cyclebase \| Genevestigator \| GermOnline \| SPELL \| YMGV \| YeastFunc

Localization	YPL+ \| YeastGFP
Phosphorylation	PhosphoGRID \| PhosphoPep Database
Structure	GPMDB \| SCOP
Homologs	Ashbya (AGD) \| Fungal Orthogroups Repository \| P-POD \| PDB Homologs \| PhylomeDB \| YGOB \| YOGY

sequence information

ChrMito:61022 to 61729 | |

This feature is contained within: 21S_RRNA

Last Update

Coordinates: 2000-05-19 | Sequence: 2000-05-19

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..708	61022..61729	2000-05-19	2000-05-19

Retrieve sequences

Analyze Sequence

S288C only	BLASTP \| ATCC/WashU Clones \| BLASTN \| Design Primers \| Restriction Fragment Map \| Restriction Fragment Sizes \| Six-Frame Translation
S288C vs. other species	Fungal Alignment \| BLASTN vs. fungi \| BLASTP at NCBI \| BLASTP vs. fungi \| Synteny Viewer
S288C vs. other strains	Strain Alignment

Resources

External Links	All Associated Seq \| E.C. \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| Search all NCBI (Entrez) \| UniProtKB

Primary SGDID	S000007279

NOMENCLATURE CONFLICT NOTE

Name	Relevance	Description
VDE	Nomenclature conflict	SceI has been used to refer to three different endonucleases: I-SceI, encoded by SCEI/OMEGA; Endo.SceI, composed of Ssc1p/Yjr045p and the mitochondrially-encoded Ens2p; and PI-SCEI/VDE, the TFP1-derived endonuclease.
ENS2	Nomenclature conflict	SceI has been used to refer to three different endonucleases: I-SceI, encoded by SCEI/OMEGA; Endo.SceI, composed of Ssc1p/Yjr045p and the mitochondrially-encoded Ens2p; and PI-SCEI/VDE, the TFP1-derived endonuclease.

1)	Zinn AR and Butow RA (1985) Nonreciprocal exchange between alleles of the yeast mitochondrial 21S rRNA gene: kinetics and the involvement of a double-strand break. Cell 40(4):887-95
2)	Macreadie IG, et al. (1985) Transposition of an intron in yeast mitochondria requires a protein encoded by that intron. Cell 41(2):395-402
3)	Jacquier A and Dujon B (1985) An intron-encoded protein is active in a gene conversion process that spreads an intron into a mitochondrial gene. Cell 41(2):383-94
4)	Perrin A, et al. (1993) Asymmetrical recognition and activity of the I-SceI endonuclease on its site and on intron-exon junctions. EMBO J 12(7):2939-47