SBE2/YDR351W Summary Help

Standard Name SBE2 1
Systematic Name YDR351W
Feature Type ORF, Verified
Description Protein required for bud growth; involved in transport of cell wall components from the Golgi to the cell surface; SBE2 has a paralog, SBE22, that arose from the whole genome duplication (2, 3, 4)
Name Description Suppressor of BEm4 3
Chromosomal Location
ChrIV:1178666 to 1181260 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All SBE2 GO evidence and references
  View Computational GO annotations for SBE2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 71 genes
Resources
Large-scale survey
null
overexpression
Resources
23 total interaction(s) for 16 unique genes/features.
Physical Interactions
  • Affinity Capture-Western: 1

Genetic Interactions
  • Dosage Growth Defect: 2
  • Dosage Rescue: 1
  • Negative Genetic: 9
  • Synthetic Growth Defect: 6
  • Synthetic Lethality: 3
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 864
Molecular Weight (Da) 98,971
Isoelectric Point (pI) 8.32
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIV:1178666 to 1181260 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..2595 1178666..1181260 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000002759
References cited on this page View Complete Literature Guide for SBE2
1) Nishimura, K., et al.,  (1995) Yeast Saccharomyces cerevisiae Genes, SBE2 and SBE22, is required for bud growth. Unpublished
2) Santos B and Snyder M  (2000) Sbe2p and sbe22p, two homologous Golgi proteins involved in yeast cell wall formation. Mol Biol Cell 11(2):435-52
3) Mack D, et al.  (1996) Identification of the bud emergence gene BEM4 and its interactions with rho-type GTPases in Saccharomyces cerevisiae. Mol Cell Biol 16(8):4387-95
4) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61