Standard Name	SAW1 1
Systematic Name	YAL027W
Feature Type	ORF, Verified
Description	5'- and 3'-flap DNA binding protein; recruits Rad1p-Rad10p to single-strand annealing intermediates with 3' non-homologous tails for removal during double-strand break repair; complexes with Rad1p-Rad10p and stimulates its endonuclease activity; green fluorescent protein (GFP)-fusion protein localizes to the nucleus (1, 2, 3, 4)
Name Description	Single-strand Annealing Weakened 1

Chromosomal Location	ChrI:94687 to 95472 | ORF Map | GBrowse

	View Computational GO annotations for SAW1
Molecular Function
Manually curated	3'-flap-structured DNA binding (IDA) 5'-flap-structured DNA binding (IDA)
Biological Process
Manually curated	double-strand break repair via single-strand annealing, removal of nonhomologous ends (IGI, IMP) positive regulation of endodeoxyribonuclease activity (IDA)
Cellular Component
High-throughput	nucleus (IDA)

Classical genetics
null	mitotic recombination: increased resistance to tellurite: decreased
Large-scale survey
null	UV resistance: decreased anaerobic growth: decreased competitive fitness: decreased resistance to fenpropimorph: decreased resistance to benzo[a]pyrene: decreased resistance to ethanol: decreased transposable element transposition: decreased vacuolar morphology: abnormal viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	64 total interaction(s) for 46 unique genes/features.
Physical Interactions	Affinity Capture-MS: 33 Affinity Capture-RNA: 2 Affinity Capture-Western: 5 Reconstituted Complex: 9 Two-hybrid: 1
Genetic Interactions	Negative Genetic: 11 Phenotypic Enhancement: 1 Positive Genetic: 1 Synthetic Lethality: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrI:94687 to 95472 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..786 94687..95472 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB382 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000000025