| Standard Name | SAD1 1 (see Nomenclature conflict Note) |
|---|---|
| Systematic Name | YFR005C |
| Feature Type | ORF, Verified |
| Description | Conserved zinc-finger domain protein involved in pre-mRNA splicing, required for assembly of U4 snRNA into the U4/U6 particle (1) |
| Name Description | SnRNP Assembly Defective 1 |
| Chromosomal Location | |
|---|---|
| Note: this feature is encoded on the Crick strand. | |
Gene Ontology Annotations All SAD1 GO evidence and references
| View Computational GO annotations for SAD1 | |
| Molecular Function | |
| Manually curated |
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| Biological Process | |
| Manually curated | |
| Cellular Component | |
| Manually curated |
Mutant phenotypes All SAD1 Phenotype evidence and references
| Large-scale survey | |
|---|---|
| conditional | |
| null | |
| reduction of function |
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| Resources |
interactions All SAD1 Interaction evidence and references
| 11 total interaction(s) for 11 unique genes/features. | |
| Physical Interactions |
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| Genetic Interactions |
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| Resources |
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Expression Summary
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| Resources |
Protein Information All SAD1 Protein evidence and references
| Localization | |
|---|---|
| Phosphorylation | PhosphoGRID | PhosphoPep Database |
| Structure | |
| Homologs |
sequence information
| Note: this feature is encoded on the Crick strand. | |||||||||||||
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| Last Update | Coordinates: 2011-02-03 | Sequence: 1996-07-31 | ||||||||||||
| Subfeature details |
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| Retrieve sequences | |||||||||||||
Analyze Sequence
| S288C only | |
|---|---|
| S288C vs. other species | |
| S288C vs. other strains |
Resources
| External Links | All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB |
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| Primary SGDID | S000001901 |
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NOMENCLATURE CONFLICT NOTE
| Name | Relevance | Description |
|---|---|---|
| RAD53 | Nomenclature conflict | SAD1 has been used to refer to both RAD53/YPL153C, a checkpoint protein involved in DNA repair, and SAD1/YFR005C, a protein involved in mRNA splicing. |
References cited on this page View Complete Literature Guide for SAD1
| 1) | Lygerou Z, et al. (1999) A novel genetic screen for snRNP assembly factors in yeast identifies a conserved protein, Sad1p, also required for pre-mRNA splicing. Mol Cell Biol 19(3):2008-20 |




