BIT2/YBR270C Summary Help

BIT2 BASIC INFORMATION

Standard Name BIT2 1, 2
Systematic Name YBR270C
Feature Type ORF, Uncharacterized
Description Subunit of TORC2, a membrane-associated complex that regulates actin cytoskeletal dynamics during polarized growth and cell wall integrity; interacts with Slm1p and Slm2p, homologous PH domain-containing TORC2 substrates; similar to Bit61p (2, 3, 4, 5)
Name Description Binding partner of Tor2p 1, 6
GO Annotations All BIT2 GO evidence and references
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All BIT2 Phenotype details and references
Classical genetics
null
Large-scale survey
null
Interactions BIT2 All interactions details and references
21 total interaction(s) for 16 unique genes/features.
Physical Interactions
  • Biochemical Activity: 4
  • Reconstituted Complex: 2
  • Two-hybrid: 14
Genetic Interactions
  • Dosage Lethality: 1
Sequence Information
ChrII:744393 to 742756 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Last Update Coordinates: 2004-07-16 | Sequence: 1997-01-28
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..1638 744393..742756 2004-07-16 1997-01-28
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000000474

BIT2 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
 GBrowse
  • Literature
  • Retrieve Sequences
  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
  • Maps & Displays
  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for BIT2

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for BIT2]

1) Shioda, R, et al.  (2005) personal communication
2) De Virgilio C and Loewith R  (2006) Cell growth control: little eukaryotes make big contributions. Oncogene 25(48):6392-415
3) Schmidt A, et al.  (1996) TOR2 is required for organization of the actin cytoskeleton in yeast. Proc Natl Acad Sci U S A 93(24):13780-5
4) Fadri M, et al.  (2005) The pleckstrin homology domain proteins Slm1 and Slm2 are required for actin cytoskeleton organization in yeast and bind phosphatidylinositol-4,5-bisphosphate and TORC2. Mol Biol Cell 16(4):1883-900
5) Rohde JR, et al.  (2008) Nutritional control via Tor signaling in Saccharomyces cerevisiae. Curr Opin Microbiol 11(2):153-60
6) Reinke A, et al.  (2004) TOR complex 1 includes a novel component, Tco89p (YPL180w), and cooperates with Ssd1p to maintain cellular integrity in Saccharomyces cerevisiae. J Biol Chem 279(15):14752-62