RIM9/YMR063W Summary Help

Standard Name RIM9 1
Systematic Name YMR063W
Feature Type ORF, Verified
Description Plasma membrane protein of unknown function; involved in the proteolytic activation of Rim101p in response to alkaline pH; interacts with Rim21p and Dfg16p to form a pH-sensing complex in the Rim101 pathway and is required to maintain Rim21p levels; has similarity to A. nidulans PalI; (2, 3, 4)
Name Description Regulator of IME2 1
Chromosomal Location
ChrXIII:397077 to 397796 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All RIM9 GO evidence and references
  View Computational GO annotations for RIM9
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 1 genes
Resources
Classical genetics
conditional
null
unspecified
Large-scale survey
null
overexpression
Resources
172 total interaction(s) for 123 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1
  • Affinity Capture-Western: 2
  • Co-purification: 1

Genetic Interactions
  • Dosage Growth Defect: 1
  • Dosage Rescue: 1
  • Negative Genetic: 133
  • Phenotypic Enhancement: 1
  • Phenotypic Suppression: 1
  • Positive Genetic: 16
  • Synthetic Growth Defect: 9
  • Synthetic Lethality: 3
  • Synthetic Rescue: 3

Resources
Expression Summary
histogram
Resources
Length (a.a.) 239
Molecular Weight (Da) 26,696
Isoelectric Point (pI) 6.22
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXIII:397077 to 397796 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..720 397077..397796 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000004667
References cited on this page View Complete Literature Guide for RIM9
1) Su SS and Mitchell AP  (1993) Identification of functionally related genes that stimulate early meiotic gene expression in yeast. Genetics 133(1):67-77
2) Li W and Mitchell AP  (1997) Proteolytic activation of Rim1p, a positive regulator of yeast sporulation and invasive growth. Genetics 145(1):63-73
3) Denison SH, et al.  (1998) Putative membrane components of signal transduction pathways for ambient pH regulation in Aspergillus and meiosis in saccharomyces are homologous. Mol Microbiol 30(2):259-64
4) Obara K, et al.  (2012) Membrane protein Rim21 plays a central role in sensing ambient pH in Saccharomyces cerevisiae. J Biol Chem 287(46):38473-81