HXT2/YMR011W Summary Help

Standard Name HXT2
Systematic Name YMR011W
Feature Type ORF, Verified
Description High-affinity glucose transporter of the major facilitator superfamily; expression is induced by low levels of glucose and repressed by high levels of glucose (1, 2)
Name Description HeXose Transporter
Chromosomal Location
ChrXIII:288079 to 289704 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All HXT2 GO evidence and references
  View Computational GO annotations for HXT2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 12 genes
Resources
Classical genetics
null
Large-scale survey
null
unspecified
Resources
123 total interaction(s) for 96 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 3
  • Affinity Capture-RNA: 3
  • Affinity Capture-Western: 1
  • Co-fractionation: 2
  • Co-purification: 1
  • PCA: 8
  • Two-hybrid: 1

Genetic Interactions
  • Dosage Rescue: 4
  • Negative Genetic: 77
  • Phenotypic Enhancement: 7
  • Phenotypic Suppression: 1
  • Positive Genetic: 11
  • Synthetic Growth Defect: 4

Resources
Expression Summary
histogram
Resources
Length (a.a.) 541
Molecular Weight (Da) 59,840
Isoelectric Point (pI) 8.31
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXIII:288079 to 289704 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1626 288079..289704 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | TCDB | UniProtKB
Primary SGDIDS000004613
References cited on this page View Complete Literature Guide for HXT2
1) Ozcan S and Johnston M  (1999) Function and regulation of yeast hexose transporters. Microbiol Mol Biol Rev 63(3):554-69
2) Ozcan S and Johnston M  (1995) Three different regulatory mechanisms enable yeast hexose transporter (HXT) genes to be induced by different levels of glucose. Mol Cell Biol 15(3):1564-72