Standard Name	SDH2 1
Systematic Name	YLL041C
Alias	ACN17
Feature Type	ORF, Verified
Description	Iron-sulfur protein subunit of succinate dehydrogenase (Sdh1p, Sdh2p, Sdh3p, Sdh4p), which couples the oxidation of succinate to the transfer of electrons to ubiquinone as part of the TCA cycle and the mitochondrial respiratory chain (2) Also known as: SDHB 3
Name Description	Succinate DeHydrogenase 1

Chromosomal Location	ChrXII:53931 to 53131 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.

	View Computational GO annotations for SDH2
Molecular Function
Manually curated	succinate dehydrogenase (ubiquinone) activity (IDA, IGI, IMP)
Biological Process
Manually curated	cellular respiration (IGI, IMP) mitochondrial electron transport, succinate to ubiquinone (TAS) tricarboxylic acid cycle (IMP)
Cellular Component
Manually curated	mitochondrial membrane (IDA) mitochondrial respiratory chain complex II (IDA)
High-throughput	mitochondrion (IDA)

Pathways	aerobic respiration, electron transport chain superpathway of TCA cycle and glyoxylate cycle TCA cycle, aerobic respiration

Classical genetics
null	reactive oxygen species accumulation: decreased reactive oxygen species accumulation: increased Sdh5p accumulation: increased respiratory growth: absent respiratory growth: decreased rate survival rate in stationary phase: increased survival rate in stationary phase: decreased toxin resistance: increased
unspecified	utilization of carbon source: absent
Large-scale survey
null	anaerobic growth: decreased competitive fitness: increased dessication resistance: decreased haploinsufficient respiratory growth: decreased rate respiratory growth: absent sporulation efficiency: decreased starvation resistance: decreased viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	64 total interaction(s) for 52 unique genes/features.
Physical Interactions	Affinity Capture-MS: 4 Affinity Capture-RNA: 2 Affinity Capture-Western: 3 Reconstituted Complex: 1
Genetic Interactions	Negative Genetic: 35 Phenotypic Suppression: 4 Positive Genetic: 13 Synthetic Growth Defect: 2
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | AspGD Homologs | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXII:53931 to 53131 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..801 53931..53131 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB382 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000003964