ADE8/YDR408C Summary Help

Standard Name ADE8
Systematic Name YDR408C
Feature Type ORF, Verified
Description Phosphoribosyl-glycinamide transformylase; catalyzes a step in the 'de novo' purine nucleotide biosynthetic pathway (1)
Name Description ADEnine requiring
Chromosomal Location
ChrIV:1288859 to 1288215 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Genetic position: 256 cM
Gene Ontology Annotations All ADE8 GO evidence and references
  View Computational GO annotations for ADE8
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Regulators 6 genes
Resources
Pathways
Classical genetics
null
Large-scale survey
null
Resources
20 total interaction(s) for 19 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 4
  • Affinity Capture-RNA: 3
  • Two-hybrid: 3

Genetic Interactions
  • Negative Genetic: 6
  • Phenotypic Suppression: 1
  • Positive Genetic: 3

Resources
Expression Summary
histogram
Resources
Length (a.a.) 214
Molecular Weight (Da) 23,540
Isoelectric Point (pI) 6.4
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIV:1288859 to 1288215 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Genetic position: 256 cM
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..645 1288859..1288215 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000002816
References cited on this page View Complete Literature Guide for ADE8
1) Jones EW and Fink GR  (1982) "Regulation of amino acid and nucleotide biosynthesis in yeast." Pp.181-299 in The Molecular Biology of the Yeast Saccharomyces: Metabolism and Gene Expression, edited by Strathern JN, Jones EW and Broach JR. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press