YSP2/YDR326C Summary Help

Standard Name YSP2 1
Systematic Name YDR326C
Feature Type ORF, Verified
Description Protein involved in programmed cell death; mutant shows resistance to cell death induced by amiodarone or intracellular acidification; YSP2 has a paralog, YHR080C, that arose from the whole genome duplication (1, 2)
Name Description Yeast Suicide Protein 1
Chromosomal Location
ChrIV:1124925 to 1120609 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All YSP2 GO evidence and references
  View Computational GO annotations for YSP2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 2 genes
Resources
Classical genetics
null
Large-scale survey
null
overexpression
unspecified
Resources
28 total interaction(s) for 24 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 7
  • Affinity Capture-RNA: 3
  • Co-purification: 1
  • Two-hybrid: 8

Genetic Interactions
  • Dosage Growth Defect: 4
  • Negative Genetic: 3
  • Synthetic Growth Defect: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 1,438
Molecular Weight (Da) 160,577
Isoelectric Point (pI) 7.47
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIV:1124925 to 1120609 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..4317 1124925..1120609 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000002734
References cited on this page View Complete Literature Guide for YSP2
1) Sokolov S, et al.  (2006) Ysp2 mediates death of yeast induced by amiodarone or intracellular acidification. Biochim Biophys Acta 1757(9-10):1366-70
2) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61