SER33/YIL074C Summary

SER33 BASIC INFORMATION

Standard Name	SER33
Systematic Name	YIL074C
Feature Type	ORF, Verified
Description	3-phosphoglycerate dehydrogenase, catalyzes the first step in serine and glycine biosynthesis; isozyme of Ser3p (1)
Name Description	SERine requiring 1

GO Annotations	All SER33 GO evidence and references
	View Computational GO annotations for SER33
Molecular Function
Manually curated	phosphoglycerate dehydrogenase activity (IMP)
Biological Process
Manually curated	serine family amino acid biosynthetic process (IMP)
Cellular Component
High-throughput	cytoplasm (IDA)

Pathways	serine biosynthesis from 3-phosphoglycerate superpathway of serine and glycine biosynthesis

Mutant Phenotype	All SER33 Phenotype details and references
Classical genetics
null	Pmp2GFP-KKTN distribution: decreased
Large-scale survey
null	Pmp2GFP-LRKR distribution: decreased viable

Interactions	SER33 All interactions details and references
	24 total interaction(s) for 13 unique genes/features.
Physical Interactions	Affinity Capture-MS: 6 Biochemical Activity: 4 Two-hybrid: 9
Genetic Interactions	Phenotypic Enhancement: 1 Synthetic Growth Defect: 2 Synthetic Lethality: 2

Sequence Information

ChrIX:222487 to 221078 | |

Note: this feature is encoded on the Crick strand.

Last Update

Coordinates: 1994-12-10 | Sequence: 1994-12-10

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..1410	222487..221078	1994-12-10	1994-12-10

External Links	All Associated Seq \| E.C. \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000001336

SER33 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for SER33

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for SER33]

1)	Albers E, et al. (2003) Ser3p (Yer081wp) and Ser33p (Yil074cp) are phosphoglycerate dehydrogenases in Saccharomyces cerevisiae. J Biol Chem 278(12):10264-72

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