CTF8/YHR191C Summary Help

Standard Name CTF8 1
Systematic Name YHR191C
Feature Type ORF, Verified
Description Subunit of a complex with Ctf18p; shares some subunits with Replication Factor C; required for sister chromatid cohesion (2)
Name Description Chromosome Transmission Fidelity 1
Chromosomal Location
ChrVIII:486631 to 486230 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All CTF8 GO evidence and references
  View Computational GO annotations for CTF8
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 4 genes
Resources
Classical genetics
null
unspecified
Large-scale survey
null
Resources
751 total interaction(s) for 348 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 6
  • Affinity Capture-RNA: 2
  • Affinity Capture-Western: 6
  • Reconstituted Complex: 1

Genetic Interactions
  • Dosage Growth Defect: 1
  • Dosage Lethality: 1
  • Dosage Rescue: 1
  • Negative Genetic: 348
  • Phenotypic Enhancement: 5
  • Phenotypic Suppression: 3
  • Positive Genetic: 46
  • Synthetic Growth Defect: 246
  • Synthetic Lethality: 83
  • Synthetic Rescue: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 133
Molecular Weight (Da) 15,169
Isoelectric Point (pI) 9.07
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrVIII:486631 to 486230 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2005-11-07 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..402 486631..486230 2005-11-07 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001234
References cited on this page View Complete Literature Guide for CTF8
1) Spencer F, et al.  (1990) Mitotic chromosome transmission fidelity mutants in Saccharomyces cerevisiae. Genetics 124(2):237-49
2) Mayer ML, et al.  (2001) Identification of RFC(Ctf18p, Ctf8p, Dcc1p): an alternative RFC complex required for sister chromatid cohesion in S. cerevisiae. Mol Cell 7(5):959-70