EFM1/YHL039W Summary Help

EFM1 BASIC INFORMATION

Standard Name EFM1 1
Systematic Name YHL039W
Feature Type ORF, Verified
Description Probable lysine methyltransferase involved in the monomethylation of eEF1A (Tef1p/Tef2p); SET-domain family member; predicted involvement in ribosome biogenesis; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm (1, 2, 3, 4)
Name Description Elongation Factor Methyltransferase 1
GO Annotations All EFM1 GO evidence and references
    View Computational GO annotations for EFM1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Mutant Phenotype All EFM1 Phenotype details and references
Classical genetics
null
Large-scale survey
null
Interactions EFM1 All interactions details and references
  View additional details at BioGRID
21 total interaction(s) for 20 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 4
  • Two-hybrid: 1
Genetic Interactions
  • Negative Genetic: 12
  • Phenotypic Enhancement: 1
  • Positive Genetic: 3
Sequence Information
ChrVIII:21780 to 23537 | ORF Map | GBrowse
Gbrowse
Last Update Coordinates: 1996-07-31 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..1758 21780..23537 1996-07-31 1996-07-31
Post-translational Modifications PhosphoGRID | PhosphoPep Database
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000001031

EFM1 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
 GBrowse
  • Literature
  • Retrieve Sequences
  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
  • Maps & Displays
  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for EFM1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for EFM1]

1) Lipson RS, et al.  (2010) Two novel methyltransferases acting upon eukaryotic elongation factor 1A in Saccharomyces cerevisiae. Arch Biochem Biophys 500(2):137-143
2) Huh WK, et al.  (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91
3) Wade CH, et al.  (2006) The budding yeast rRNA and ribosome biosynthesis (RRB) regulon contains over 200 genes. Yeast 23(4):293-306
4) Porras-Yakushi TR, et al.  (2006) A novel SET domain methyltransferase in yeast: Rkm2-dependent trimethylation of ribosomal protein L12ab at lysine 10. J Biol Chem 281(47):35835-45