Standard Name	BUD16 1
Systematic Name	YEL029C
Feature Type	ORF, Verified
Description	Putative pyridoxal kinase, a key enzyme involved in pyridoxal 5'-phosphate synthesis, the active form of vitamin B6; required for genome integrity; involved in bud-site selection; similarity to yeast BUD17 and human pyridoxal kinase (PDXK) (1, 2, 3, 4)
Name Description	BUD site selection 1

Chromosomal Location	ChrV:97796 to 96858 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.

	View Computational GO annotations for BUD16
Molecular Function
Manually curated	pyridoxal kinase activity (ISA)
Biological Process
Manually curated	pyridoxal phosphate biosynthetic process (IGI, IMP)
High-throughput	cellular bud site selection (IMP)
Cellular Component
Manually curated	cytoplasm (IDA)

Pathways	pyridoxal 5'-phosphate salvage pathway

Classical genetics
null	cell cycle progression in G1 phase: increased duration cell size: decreased pyridoxal 5'-phosphate accumulation: decreased chromosome/plasmid maintenance: abnormal growth in exponential phase: decreased rate Rad52-YFP distribution: increased Rad53p modification: increased resistance to hydroxyurea: decreased
Large-scale survey
null	auxotrophy budding pattern: abnormal cell shape: abnormal cell size: increased chitin deposition: normal competitive fitness: decreased heat sensitivity: increased hyperosmotic stress resistance: decreased metal resistance: decreased resistance to doxorubicin: decreased resistance to acetic acid: decreased resistance to ethanol: decreased respiratory growth: decreased rate stress resistance: decreased telomere length: decreased toxin resistance: decreased utilization of nitrogen source: absent vacuolar morphology: abnormal vegetative growth: decreased rate viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	20 total interaction(s) for 19 unique genes/features.
Physical Interactions	Reconstituted Complex: 8 Two-hybrid: 1
Genetic Interactions	Phenotypic Enhancement: 1 Phenotypic Suppression: 1 Synthetic Growth Defect: 7 Synthetic Lethality: 2
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | AspGD Homologs | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrV:97796 to 96858 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
Last Update	Coordinates: 1996-07-31 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..939 97796..96858 1996-07-31 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000000755