SPO7/YAL009W Summary Help

Standard Name SPO7 1
Systematic Name YAL009W
Feature Type ORF, Verified
Description Putative regulatory subunit of Nem1p-Spo7p phosphatase holoenzyme; regulates nuclear growth by controlling phospholipid biosynthesis, required for normal nuclear envelope morphology, premeiotic replication, and sporulation (2, 3, 4)
Name Description SPOrulation 5
Chromosomal Location
ChrI:135854 to 136633 | ORF Map | GBrowse
Gbrowse
Genetic position: -4 cM
Gene Ontology Annotations All SPO7 GO evidence and references
  View Computational GO annotations for SPO7
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 2 genes
Resources
Classical genetics
conditional
null
Large-scale survey
null
Resources
101 total interaction(s) for 78 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 6
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 1
  • Biochemical Activity: 2
  • PCA: 1

Genetic Interactions
  • Dosage Growth Defect: 1
  • Dosage Rescue: 2
  • Negative Genetic: 40
  • Phenotypic Enhancement: 10
  • Phenotypic Suppression: 1
  • Positive Genetic: 2
  • Synthetic Growth Defect: 15
  • Synthetic Lethality: 19

Resources
Expression Summary
histogram
Resources
Length (a.a.) 259
Molecular Weight (Da) 30,113
Isoelectric Point (pI) 10.84
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrI:135854 to 136633 | ORF Map | GBrowse
SGD ORF map
Genetic position: -4 cM
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..780 135854..136633 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000000007
References cited on this page View Complete Literature Guide for SPO7
1) Esposito, R.E. and Waddell, C.  (1985) Personal Communication, Mortimer Map Edition 9
2) Siniossoglou S, et al.  (1998) A novel complex of membrane proteins required for formation of a spherical nucleus. EMBO J 17(22):6449-64
3) Esposito MS and Esposito RE  (1974) Genes controlling meiosis and spore formation in yeast. Genetics 78(1):215-25
4) Santos-Rosa H, et al.  (2005) The yeast lipin Smp2 couples phospholipid biosynthesis to nuclear membrane growth. EMBO J 24(11):1931-41
5) Esposito MS, et al.  (1970) Conditional mutants of meiosis in yeast. J Bacteriol 104(1):202-10