ROM1/YGR070W Summary Help

Standard Name ROM1 1
Systematic Name YGR070W
Alias SKC1
Feature Type ORF, Verified
Description GDP/GTP exchange protein (GEP) for Rho1p; mutations are synthetically lethal with mutations in rom2, which also encodes a GEP; ROM1 has a paralog, ROM2, that arose from the whole genome duplication (1, 2)
Name Description RhO1 Multicopy suppressor 1
Chromosomal Location
ChrVII:627806 to 631273 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All ROM1 GO evidence and references
  View Computational GO annotations for ROM1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 2 genes
Resources
Classical genetics
null
Large-scale survey
null
unspecified
Resources
49 total interaction(s) for 39 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 4
  • Affinity Capture-RNA: 2
  • Two-hybrid: 1

Genetic Interactions
  • Dosage Rescue: 3
  • Negative Genetic: 15
  • Phenotypic Enhancement: 1
  • Phenotypic Suppression: 6
  • Positive Genetic: 1
  • Synthetic Growth Defect: 3
  • Synthetic Lethality: 5
  • Synthetic Rescue: 8

Resources
Expression Summary
histogram
Resources
Length (a.a.) 1,155
Molecular Weight (Da) 131,419
Isoelectric Point (pI) 9.45
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrVII:627806 to 631273 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 2011-02-03
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..3468 627806..631273 2011-02-03 2011-02-03
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000003302
References cited on this page View Complete Literature Guide for ROM1
1) Ozaki K, et al.  (1996) Rom1p and Rom2p are GDP/GTP exchange proteins (GEPs) for the Rho1p small GTP binding protein in Saccharomyces cerevisiae. EMBO J 15(9):2196-207
2) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61