Standard Name	RXT3 1, 2
Systematic Name	YDL076C
Feature Type	ORF, Verified
Description	Subunit of the RPD3L complex; involved in histone deacetylation; protein abundance increases in response to DNA replication stress (2, 3, 4)

Chromosomal Location	ChrIV:321552 to 320668 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.

	View Computational GO annotations for RXT3
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	negative regulation of transcription from RNA polymerase I promoter (IMP)
Cellular Component
Manually curated	Rpd3L complex (IDA)
High-throughput	nucleus (IDA) Rpd3L complex (IDA) Rpd3L-Expanded complex (IDA)

Classical genetics
null	viable
Large-scale survey
null	polyphosphate accumulation: abnormal competitive fitness: increased dessication resistance: decreased haploproficient resistance to tunicamycin: increased resistance to cycloheximide: increased resistance to propolis extract: decreased resistance to bleomycin: decreased resistance to caffeine: decreased resistance to fluconazole: decreased resistance to hydroxyurea: increased sporulation: normal toxin resistance: increased vacuolar morphology: abnormal viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	133 total interaction(s) for 96 unique genes/features.
Physical Interactions	Affinity Capture-MS: 45 Affinity Capture-RNA: 4 Affinity Capture-Western: 1 Two-hybrid: 3
Genetic Interactions	Negative Genetic: 64 Positive Genetic: 16
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrIV:321552 to 320668 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
Last Update	Coordinates: 2004-02-11 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..885 321552..320668 2004-02-11 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000002234