RTS1/YOR014W Summary Help

RTS1 BASIC INFORMATION

Standard Name RTS1
Systematic Name YOR014W
Alias SCS1 1
Feature Type ORF, Verified
Description B-type regulatory subunit of protein phosphatase 2A (PP2A); homolog of the mammalian B' subunit of PP2A (2, 3)
GO Annotations All RTS1 GO evidence and references
    View Computational GO annotations for RTS1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Mutant Phenotype All RTS1 Phenotype details and references
Classical genetics
null
Large-scale survey
null
Interactions RTS1 All interactions details and references
140 total interaction(s) for 108 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 20
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 3
  • Biochemical Activity: 2
  • PCA: 1
  • Two-hybrid: 2

Genetic Interactions
  • Dosage Rescue: 2
  • Phenotypic Enhancement: 68
  • Phenotypic Suppression: 21
  • Synthetic Growth Defect: 8
  • Synthetic Haploinsufficiency: 1
  • Synthetic Lethality: 7
  • Synthetic Rescue: 4

Sequence Information
ChrXV:357674 to 359947 | ORF Map | GBrowse
Gbrowse
Last Update Coordinates: 2006-01-05 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..2274 357674..359947 2006-01-05 1996-07-31
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000005540

RTS1 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
  • Maps & Displays
  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

NOMENCLATURE CONFLICT NOTE

NameRelevanceDescription
LCB2Nomenclature conflictSCS1 has been used in the literature to refer to both RTS1/YOR014W, which encodes a protein phosphatase 2A and LCB2/YDR062W, which encodes a serine C-palmitoyltransferase.
INO2Nomenclature conflictSCS1 has been used in the literature to refer to both RTS1/YOR014W, which encodes a protein phosphatase 2A and INO2/YDR123C, which encodes a RNA Pol II transcription factor.

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for RTS1]

1) Shu Y and Hallberg RL  (1995) SCS1, a multicopy suppressor of hsp60-ts mutant alleles, does not encode a mitochondrially targeted protein. Mol Cell Biol 15(10):5618-26
2) Zhao Y, et al.  (1997) Saccharomyces cerevisiae homologs of mammalian B and B' subunits of protein phosphatase 2A direct the enzyme to distinct cellular functions. J Biol Chem 272(13):8256-62
3) Shu Y, et al.  (1997) Molecular genetic analysis of Rts1p, a B' regulatory subunit of Saccharomyces cerevisiae protein phosphatase 2A. Mol Cell Biol 17(6):3242-53