Standard Name	RTG1 1
Systematic Name	YOL067C
Feature Type	ORF, Verified
Description	Transcription factor (bHLH) involved in interorganelle communication between mitochondria, peroxisomes, and nucleus (1, 2, 3, 4)
Name Description	ReTroGrade regulation 1

Chromosomal Location	ChrXV:202518 to 201985 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.

	View Computational GO annotations for RTG1
Molecular Function
Manually curated	sequence-specific DNA binding RNA polymerase II transcription factor activity (IDA, IMP)
Biological Process
Manually curated	cellular response to oleic acid (IMP) mitochondria-nucleus signaling pathway (IDA, IMP) positive regulation of transcription from RNA polymerase II promoter (IDA, IMP)
Cellular Component
Manually curated	cytoplasm (IDA) nucleus (IDA)

Resources	ScerTF | YEASTRACT | YeTFaSCo

Classical genetics
null	auxotrophy resistance to pterostilbene: increased resistance to hydroxyurea: decreased utilization of carbon source: decreased
Large-scale survey
null	auxotrophy competitive fitness: decreased dessication resistance: decreased haploinsufficient heat sensitivity: increased resistance to sulfanilamide: decreased resistance to mycophenolic acid: increased resistance to fluconazole: increased resistance to fenpropimorph: increased resistance to camptothecin: increased resistance to nickel sulfate: increased resistance to hydroxyurea: decreased resistance to ethanol: decreased resistance to bleomycin: decreased resistance to caffeine: decreased resistance to sodium selenide: decreased resistance to cycloheximide: increased resistance to doxorubicin: decreased resistance to hygromycin B: decreased vacuolar morphology: abnormal viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	322 total interaction(s) for 237 unique genes/features.
Physical Interactions	Affinity Capture-MS: 5 Affinity Capture-Western: 2 Co-localization: 1 Reconstituted Complex: 1 Two-hybrid: 3
Genetic Interactions	Negative Genetic: 223 Phenotypic Enhancement: 1 Phenotypic Suppression: 5 Positive Genetic: 73 Synthetic Growth Defect: 5 Synthetic Lethality: 1 Synthetic Rescue: 2
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXV:202518 to 201985 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
Last Update	Coordinates: 2006-01-05 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..534 202518..201985 2006-01-05 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain CLIB382 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000005428