RTC4/YNL254C Summary Help

Standard Name RTC4 1
Systematic Name YNL254C
Feature Type ORF, Verified
Description Protein of unknown function; null mutation suppresses cdc13-1 temperature sensitivity; (GFP)-fusion protein localizes to both the cytoplasm and the nucleus (1, 2)
Name Description Restriction of Telomere Capping 1
Chromosomal Location
ChrXIV:169248 to 168043 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All RTC4 GO evidence and references
  View Computational GO annotations for RTC4
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Regulators 47 genes
Resources
Classical genetics
null
Large-scale survey
null
overexpression
Resources
9 total interaction(s) for 9 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 3

Genetic Interactions
  • Positive Genetic: 1
  • Synthetic Growth Defect: 3
  • Synthetic Lethality: 1
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 401
Molecular Weight (Da) 46,211
Isoelectric Point (pI) 7.46
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXIV:169248 to 168043 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1206 169248..168043 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005198
References cited on this page View Complete Literature Guide for RTC4
1) Addinall SG, et al.  (2008) A Genomewide Suppressor and Enhancer Analysis of cdc13-1 Reveals Varied Cellular Processes Influencing Telomere Capping in Saccharomyces cerevisiae. Genetics 180(4):2251-66
2) Huh WK, et al.  (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91