RSC9/YML127W Summary Help

Standard Name RSC9 1
Systematic Name YML127W
Feature Type ORF, Verified
Description Component of the RSC chromatin remodeling complex; DNA-binding protein involved in the synthesis of rRNA and in transcriptional repression and activation of genes regulated by the Target of Rapamycin (TOR) pathway (1, 2, 3)
Name Description Remodel the Structure of Chromatin 1, 4
Chromosomal Location
ChrXIII:17064 to 18809 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All RSC9 GO evidence and references
  View Computational GO annotations for RSC9
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 6 genes
Resources
Classical genetics
repressible
Large-scale survey
conditional
null
repressible
Resources
125 total interaction(s) for 58 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 81
  • Affinity Capture-Western: 4
  • Co-purification: 1
  • Reconstituted Complex: 4
  • Two-hybrid: 1

Genetic Interactions
  • Negative Genetic: 21
  • Synthetic Growth Defect: 7
  • Synthetic Lethality: 5
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 581
Molecular Weight (Da) 65,217
Isoelectric Point (pI) 7.8
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXIII:17064 to 18809 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1746 17064..18809 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000004596
References cited on this page View Complete Literature Guide for RSC9
1) Damelin M, et al.  (2002) The genome-wide localization of Rsc9, a component of the RSC chromatin-remodeling complex, changes in response to stress. Mol Cell 9(3):563-73
2) Lorch Y, et al.  (1998) Activated RSC-nucleosome complex and persistently altered form of the nucleosome. Cell 94(1):29-34
3) Neely KE and Workman JL  (2002) The complexity of chromatin remodeling and its links to cancer. Biochim Biophys Acta 1603(1):19-29
4) Cairns BR, et al.  (1996) RSC, an essential, abundant chromatin-remodeling complex. Cell 87(7):1249-60