Standard Name	RSC9 1
Systematic Name	YML127W
Feature Type	ORF, Verified
Description	Component of the RSC chromatin remodeling complex; DNA-binding protein involved in the synthesis of rRNA and in transcriptional repression and activation of genes regulated by the Target of Rapamycin (TOR) pathway (1, 2, 3)
Name Description	Remodel the Structure of Chromatin 1, 4

Chromosomal Location	ChrXIII:17064 to 18809 | ORF Map | GBrowse

	View Computational GO annotations for RSC9
Molecular Function
Manually curated	chromatin binding (IPI) contributes_to DNA translocase activity (IDA)
Biological Process
Manually curated	ATP-dependent chromatin remodeling (IDA) chromatin remodeling (IPI) G2/M transition of mitotic cell cycle (IMP) nucleosome disassembly (IDA) regulation of transcription from RNA polymerase II promoter (IMP) response to stress (IDA) rRNA transcription (IMP) transcription elongation from RNA polymerase II promoter (IDA)
Cellular Component
Manually curated	RSC complex (IDA)

Classical genetics
repressible	cell cycle progression through the G2/M phase transition: arrested
Large-scale survey
conditional	heat sensitivity: increased
null	inviable
repressible	mitochondrial morphology: abnormal
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	122 total interaction(s) for 56 unique genes/features.
Physical Interactions	Affinity Capture-MS: 78 Affinity Capture-Western: 4 Co-purification: 1 Reconstituted Complex: 4 Two-hybrid: 1
Genetic Interactions	Negative Genetic: 21 Synthetic Growth Defect: 7 Synthetic Lethality: 5 Synthetic Rescue: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | AspGD Homologs | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXIII:17064 to 18809 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1746 17064..18809 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain EC1118 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000004596