RRN7/YJL025W Summary Help

Standard Name RRN7 1
Systematic Name YJL025W
Feature Type ORF, Verified
Description Component of the core factor (CF) rDNA transcription factor complex; CF is required for transcription of 35S rRNA genes by RNA polymerase I and is composed of Rrn6p, Rrn7p, and Rrn11p (2, 3, 4)
Name Description Regulation of RNA polymerase I 1
Chromosomal Location
ChrX:393967 to 395511 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All RRN7 GO evidence and references
  View Computational GO annotations for RRN7
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 4 genes
Resources
Classical genetics
conditional
Large-scale survey
conditional
null
reduction of function
Resources
29 total interaction(s) for 17 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1
  • Affinity Capture-RNA: 2
  • Affinity Capture-Western: 7
  • Co-purification: 1
  • Protein-RNA: 1
  • Reconstituted Complex: 1
  • Two-hybrid: 12

Genetic Interactions
  • Synthetic Lethality: 4

Resources
Expression Summary
histogram
Resources
Length (a.a.) 514
Molecular Weight (Da) 60,357
Isoelectric Point (pI) 8.12
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrX:393967 to 395511 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1545 393967..395511 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000003562
References cited on this page View Complete Literature Guide for RRN7
1) Nogi Y, et al.  (1991) An approach for isolation of mutants defective in 35S ribosomal RNA synthesis in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 88(16):7026-30
2) Lin CW, et al.  (1996) A novel 66-kilodalton protein complexes with Rrn6, Rrn7, and TATA-binding protein to promote polymerase I transcription initiation in Saccharomyces cerevisiae. Mol Cell Biol 16(11):6436-43
3) Keys DA, et al.  (1994) RRN6 and RRN7 encode subunits of a multiprotein complex essential for the initiation of rDNA transcription by RNA polymerase I in Saccharomyces cerevisiae. Genes Dev 8(19):2349-62
4) Lalo D, et al.  (1996) RRN11 encodes the third subunit of the complex containing Rrn6p and Rrn7p that is essential for the initiation of rDNA transcription by yeast RNA polymerase I. J Biol Chem 271(35):21062-7