RRB1/YMR131C Summary Help

Standard Name RRB1 1
Systematic Name YMR131C
Feature Type ORF, Verified
Description Nuclear protein involved in early steps of ribosome biogenesis; physically interacts with the ribosomal protein Rpl3p; essential gene (1, 2)
Name Description Regulator of Ribosome Biogenesis 1
Chromosomal Location
ChrXIII:534698 to 533163 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All RRB1 GO evidence and references
  View Computational GO annotations for RRB1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 5 genes
Resources
Classical genetics
overexpression
Large-scale survey
null
reduction of function
Resources
36 total interaction(s) for 33 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 20
  • Affinity Capture-RNA: 2
  • Affinity Capture-Western: 2
  • Co-purification: 1

Genetic Interactions
  • Dosage Rescue: 3
  • Negative Genetic: 4
  • Positive Genetic: 3
  • Synthetic Lethality: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 511
Molecular Weight (Da) 57,261
Isoelectric Point (pI) 4.31
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXIII:534698 to 533163 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1536 534698..533163 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000004738
References cited on this page View Complete Literature Guide for RRB1
1) Iouk TL, et al.  (2001) Rrb1p, a yeast nuclear WD-repeat protein involved in the regulation of ribosome biosynthesis. Mol Cell Biol 21(4):1260-71
2) Schaper S, et al.  (2001) A yeast homolog of chromatin assembly factor 1 is involved in early ribosome assembly. Curr Biol 11(23):1885-90