RPR1 Summary

RPR1 Summary

Standard Name	RPR1
Feature Type	ncRNA
Description	RNA component of nuclear RNase P; nuclear RNase P cleaves tRNA precursors to generate mature 5' ends and facilitates turnover of nuclear RNAs; may be responsible for recognition of substrate tRNAs (1, 2, 3, 4)
Name Description	RNase P RNA component 1

Chromosomal Location	ChrV:118035 to 117667 \| ORF Map \| GBrowse
	Note: this feature is encoded on the Crick strand.

	Genetic position: -6 cM

Gene Ontology Annotations All RPR1 GO evidence and references


Molecular Function
Manually curated	contributes_to ribonuclease P activity (IDA, IMP)
Biological Process
Manually curated	intronic box C/D snoRNA processing (IDA, IMP) tRNA processing (IDA, IMP)
Cellular Component
Manually curated	nucleolar ribonuclease P complex (IDA)

Mutant phenotypes All RPR1 Phenotype evidence and references

Classical genetics
reduction of function	heat sensitivity: increased

interactions All RPR1 Interaction evidence and references

	4 total interaction(s) for 4 unique genes/features.
Physical Interactions	Protein-RNA: 4

sequence information

ChrV:118035 to 117667 | |

Note: this feature is encoded on the Crick strand.

SGD ORF map

: -6 cM

Last Update

Coordinates: 2000-05-19 | Sequence: 2000-05-19

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
Noncoding exon	1..369	118035..117667	2000-05-19	2000-05-19

Retrieve sequences

Analyze Sequence

S288C only	ATCC/WashU Clones \| BLASTN \| Design Primers \| Restriction Fragment Map \| Restriction Fragment Sizes
S288C vs. other species	BLASTN vs. fungi

Resources

External Links	All Associated Seq \| Search all NCBI (Entrez)

Primary SGDID	S000006490

References cited on this page View Complete Literature Guide for RPR1

1)	Lee JY, et al. (1991) Characterization of RPR1, an essential gene encoding the RNA component of Saccharomyces cerevisiae nuclear RNase P. Mol Cell Biol 11(2):721-30
2)	Houser-Scott F, et al. (2002) Interactions among the protein and RNA subunits of Saccharomyces cerevisiae nuclear RNase P. Proc Natl Acad Sci U S A 99(5):2684-9
3)	Srisawat C, et al. (2002) An active precursor in assembly of yeast nuclear ribonuclease P. RNA 8(10):1348-60
4)	Marvin MC, et al. (2011) Accumulation of noncoding RNA due to an RNase P defect in Saccharomyces cerevisiae. RNA 17(8):1441-50