Standard Name	RNA1
Systematic Name	YMR235C
Feature Type	ORF, Verified
Description	GTPase activating protein (GAP) for Gsp1p, involved in nuclear transport (1, 2)
Name Description	RaN GTPase Activating protein

Chromosomal Location	ChrXIII:742735 to 741512 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
	Genetic position: 159 cM

	View Computational GO annotations for RNA1
Molecular Function
Manually curated	Ran GTPase activator activity (IDA, IMP)
Biological Process
Manually curated	chromatin silencing at telomere (IMP) protein import into nucleus (IDA) ribosomal subunit export from nucleus (IMP) RNA import into nucleus (IMP) rRNA export from nucleus (IMP) rRNA metabolic process (IMP) tRNA metabolic process (IMP)
Cellular Component
Manually curated	cytosol (IDA) nucleus (IDA)
High-throughput	integral to membrane (ISM)

Classical genetics
conditional	precursor tRNA accumulation: abnormal precursor rRNA accumulation: abnormal heat sensitivity: increased nuclear export: decreased nuclear import: decreased
null	inviable
repressible	5′ETS-A0 fragment of pre-rRNA accumulation: increased
Large-scale survey
conditional	chromosome/plasmid maintenance: abnormal
null	inviable
overexpression	colony sectoring: increased
reduction of function	competitive fitness: decreased resistance to benomyl: decreased
Resources	PROPHECY | PhenoM | SCMD | ScreenTroll | Yeast Fitness Database

	164 total interaction(s) for 147 unique genes/features.
Physical Interactions	Affinity Capture-MS: 24 Affinity Capture-RNA: 2 Affinity Capture-Western: 3 Biochemical Activity: 3 PCA: 1 Reconstituted Complex: 7 Two-hybrid: 25
Genetic Interactions	Dosage Lethality: 2 Dosage Rescue: 4 Negative Genetic: 68 Phenotypic Enhancement: 1 Positive Genetic: 10 Synthetic Growth Defect: 1 Synthetic Lethality: 8 Synthetic Rescue: 5
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXIII:742735 to 741512 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
	Genetic position: 159 cM
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1224 742735..741512 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000004848