RKM5/YLR137W Summary Help

Standard Name RKM5 1
Systematic Name YLR137W
Feature Type ORF, Verified
Description Protein lysine methyltransferase; monomethylates Lys-46 of the ribosomal large subunit Rpl1a/Rpl1b; member of the seven beta-strand methyltransferase superfamily; orthologs only found among fungal species (1, 2)
Name Description Ribosomal lysine (K) Methyltransferase 5 1
Chromosomal Location
ChrXII:417006 to 418109 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All RKM5 GO evidence and references
  View Computational GO annotations for RKM5
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 9 genes
Resources
Classical genetics
null
Large-scale survey
null
Resources
11 total interaction(s) for 9 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 2
  • Affinity Capture-RNA: 1
  • Biochemical Activity: 2
  • Co-purification: 1
  • Protein-peptide: 2

Genetic Interactions
  • Negative Genetic: 3

Resources
Expression Summary
histogram
Resources
Length (a.a.) 367
Molecular Weight (Da) 41,392
Isoelectric Point (pI) 6.26
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXII:417006 to 418109 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1104 417006..418109 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000004127
References cited on this page View Complete Literature Guide for RKM5
1) Webb KJ, et al.  (2011) The ribosomal l1 protuberance in yeast is methylated on a lysine residue catalyzed by a seven-beta-strand methyltransferase. J Biol Chem 286(21):18405-13
2) Petrossian TC and Clarke SG  (2009) Multiple Motif Scanning to identify methyltransferases from the yeast proteome. Mol Cell Proteomics 8(7):1516-26