RKM1/YPL208W Summary Help

Standard Name RKM1 1
Systematic Name YPL208W
Feature Type ORF, Verified
Description SET-domain lysine-N-methyltransferase; catalyzes the formation of dimethyllysine residues on the large ribsomal subunit proteins L23a (Rpl23Ap and Rpl23Bp) and L18 (Rps18Ap and Rps18Bp) (1, 2)
Name Description Ribosomal lysine (K) Methyltransferase 1
Chromosomal Location
ChrXVI:157842 to 159593 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All RKM1 GO evidence and references
  View Computational GO annotations for RKM1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Regulators 3 genes
Resources
Classical genetics
null
Large-scale survey
null
overexpression
Resources
27 total interaction(s) for 18 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 15
  • Affinity Capture-RNA: 1
  • Two-hybrid: 2

Genetic Interactions
  • Negative Genetic: 5
  • Positive Genetic: 1
  • Synthetic Growth Defect: 2
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 583
Molecular Weight (Da) 67,178
Isoelectric Point (pI) 4.86
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXVI:157842 to 159593 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1752 157842..159593 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000006129
References cited on this page View Complete Literature Guide for RKM1
1) Porras-Yakushi TR, et al.  (2005) A novel SET domain methyltransferase modifies ribosomal protein Rpl23ab in yeast. J Biol Chem 280(41):34590-8
2) Couttas TA, et al.  (2012) Methylation of translation-associated proteins in Saccharomyces cerevisiae: Identification of methylated lysines and their methyltransferases. Proteomics 12(7):960-72