Standard Name	RIM20 1
Systematic Name	YOR275C
Feature Type	ORF, Verified
Description	Protein involved in proteolytic activation of Rim101p in response to alkaline pH; PalA/AIP1/Alix family member; interaction with the ESCRT-III subunit Snf7p suggests a relationship between pH response and multivesicular body formation (1, 2)
Name Description	Regulator of IME2 3

Chromosomal Location	ChrXV:841069 to 839084 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.

	View Computational GO annotations for RIM20
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	invasive growth in response to glucose limitation (IMP) protein processing (IDA, IGI, IMP) proteolysis (IMP) response to pH (IMP) sporulation resulting in formation of a cellular spore (IMP)
Cellular Component
High-throughput	cytoplasm (IDA) nucleus (IDA)

Classical genetics
null	metal resistance: increased Nrg1p-3HA accumulation: increased resistance to 2-deoxy-D-glucose: increased resistance to Calcofluor White: increased resistance to lithium chloride: decreased resistance to BPS: decreased utilization of carbon source: decreased
Large-scale survey
null	anaerobic growth: decreased N-acetyl ornithine accumulation: increased competitive fitness: decreased endocytosis: decreased haploinsufficient hyperosmotic stress resistance: decreased ionic stress resistance: decreased oxidative stress resistance: decreased resistance to cycloheximide: decreased resistance to amitrole: decreased resistance to sirolimus: decreased resistance to ethanol: decreased resistance to methyl methanesulfonate: decreased resistance to fluconazole: decreased resistance to bleomycin: decreased resistance to camptothecin: decreased resistance to fenpropimorph: decreased resistance to hydroxyurea: decreased resistance to tunicamycin: decreased resistance to BPS: decreased resistance to wortmannin: decreased starvation resistance: decreased stress resistance: increased toxin resistance: decreased transposable element transposition: decreased viable
overexpression	vegetative growth: decreased rate
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	230 total interaction(s) for 157 unique genes/features.
Physical Interactions	Affinity Capture-Western: 1 Biochemical Activity: 1 Two-hybrid: 11
Genetic Interactions	Dosage Growth Defect: 2 Dosage Lethality: 2 Negative Genetic: 151 Positive Genetic: 24 Synthetic Growth Defect: 28 Synthetic Lethality: 10
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | AspGD Homologs | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXV:841069 to 839084 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1986 841069..839084 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000005801