RGL1/YPL066W Summary Help

Standard Name RGL1 1
Systematic Name YPL066W
Feature Type ORF, Verified
Description Regulator of Rho1p signaling, cofactor of Tus1p; required for the localization of Tus1p during all phases of cytokinesis; green fluorescent protein (GFP)-fusion protein localizes to the bud neck and cytoplasm; null mutant is viable and exhibits growth defect on a non-fermentable (respiratory) carbon source (1, 2, 3)
Name Description Rho1 GEF Localizing 1
Chromosomal Location
ChrXVI:426233 to 427672 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All RGL1 GO evidence and references
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Regulators 5 genes
Resources
Large-scale survey
null
Resources
62 total interaction(s) for 51 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 10
  • Affinity Capture-RNA: 2
  • Co-localization: 1

Genetic Interactions
  • Negative Genetic: 41
  • Phenotypic Suppression: 1
  • Positive Genetic: 4
  • Synthetic Growth Defect: 1
  • Synthetic Lethality: 1
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 479
Molecular Weight (Da) 54,893
Isoelectric Point (pI) 10.19
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXVI:426233 to 427672 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1440 426233..427672 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005987
References cited on this page View Complete Literature Guide for RGL1
1) Krause SA, et al.  (2012) Functional specialisation of yeast Rho1 GTP exchange factors. J Cell Sci 125(Pt 11):2721-31
2) Steinmetz LM, et al.  (2002) Systematic screen for human disease genes in yeast. Nat Genet 31(4):400-4
3) Huh WK, et al.  (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91