RGD1/YBR260C Summary Help

Standard Name RGD1 1
Systematic Name YBR260C
Feature Type ORF, Verified
Description GTPase-activating protein (RhoGAP) for Rho3p and Rho4p; possibly involved in control of actin cytoskeleton organization (1, 2)
Name Description Related GAP Domain 1
Chromosomal Location
ChrII:734639 to 732639 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All RGD1 GO evidence and references
  View Computational GO annotations for RGD1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 3 genes
Resources
Classical genetics
null
Large-scale survey
null
overexpression
Resources
207 total interaction(s) for 144 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 11
  • Affinity Capture-Western: 2
  • Biochemical Activity: 1
  • Co-purification: 1
  • Two-hybrid: 14

Genetic Interactions
  • Dosage Lethality: 1
  • Dosage Rescue: 7
  • Negative Genetic: 138
  • Phenotypic Enhancement: 1
  • Phenotypic Suppression: 1
  • Positive Genetic: 7
  • Synthetic Growth Defect: 7
  • Synthetic Lethality: 13
  • Synthetic Rescue: 3

Resources
Expression Summary
histogram
Resources
Length (a.a.) 666
Molecular Weight (Da) 74,618
Isoelectric Point (pI) 8.56
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrII:734639 to 732639 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1997-01-28
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..2001 734639..732639 2011-02-03 1997-01-28
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000000464
References cited on this page View Complete Literature Guide for RGD1
1) Barthe C, et al.  (1998) First characterization of the gene RGD1 in the yeast Saccharomyces cerevisiae. C R Acad Sci III 321(6):453-62
2) Roumanie O, et al.  (2000) Evidence for the genetic interaction between the actin-binding protein Vrp1 and the RhoGAP Rgd1 mediated through Rho3p and Rho4p in Saccharomyces cerevisiae. Mol Microbiol 36(6):1403-14