REC114/YMR133W Summary Help

Standard Name REC114 1
Systematic Name YMR133W
Feature Type ORF, Verified
Description Protein involved in early stages of meiotic recombination; possibly involved in the coordination of recombination and meiotic division; mutations lead to premature initiation of the first meiotic division (1, 2, 3)
Name Description RECombination 1
Chromosomal Location
ChrXIII:536207 to 537609 | ORF Map | GBrowse
Gbrowse
Genetic position: 91 cM
Gene Ontology Annotations All REC114 GO evidence and references
  View Computational GO annotations for REC114
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 3 genes
Resources
Classical genetics
reduction of function
Large-scale survey
null
overexpression
Resources
21 total interaction(s) for 15 unique genes/features.
Physical Interactions
  • Affinity Capture-Western: 2
  • Two-hybrid: 8

Genetic Interactions
  • Dosage Rescue: 1
  • Negative Genetic: 5
  • Phenotypic Enhancement: 1
  • Phenotypic Suppression: 1
  • Positive Genetic: 2
  • Synthetic Lethality: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 428
Molecular Weight (Da) 48,706
Isoelectric Point (pI) 9.86
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXIII:536207 to 537609 | ORF Map | GBrowse
SGD ORF map
Genetic position: 91 cM
Last Update Coordinates: 2011-02-03 | Sequence: 1999-07-17
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1242 536207..537448 2011-02-03 1999-07-17
Intron 1243..1358 537449..537564 2011-02-03 1999-07-17
CDS 1359..1403 537565..537609 2011-02-03 1999-07-17
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000004740
References cited on this page View Complete Literature Guide for REC114
1) Malone RE, et al.  (1991) Isolation of mutants defective in early steps of meiotic recombination in the yeast Saccharomyces cerevisiae. Genetics 128(1):79-88
2) Galbraith AM, et al.  (1997) Recombination and the progression of meiosis in Saccharomyces cerevisiae. Genetics 146(2):481-9
3) Bishop DK, et al.  (1999) High copy number suppression of the meiotic arrest caused by a dmc1 mutation: REC114 imposes an early recombination block and RAD54 promotes a DMC1-independent DSB repair pathway. Genes Cells 4(8):425-44