REC104/YHR157W Summary Help

Standard Name REC104 1
Systematic Name YHR157W
Feature Type ORF, Verified
Description Protein involved in early stages of meiotic recombination; required for meiotic crossing over; forms a complex with Rec102p and Spo11p necessary during the initiation of recombination (1, 2, 3)
Name Description RECombination 1
Chromosomal Location
ChrVIII:412907 to 413455 | ORF Map | GBrowse
Gbrowse
Genetic position: 107 cM
Gene Ontology Annotations All REC104 GO evidence and references
  View Computational GO annotations for REC104
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 6 genes
Resources
Classical genetics
null
reduction of function
Large-scale survey
null
Resources
50 total interaction(s) for 40 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 2
  • Biochemical Activity: 5
  • Two-hybrid: 8

Genetic Interactions
  • Dosage Rescue: 4
  • Negative Genetic: 23
  • Positive Genetic: 1
  • Synthetic Growth Defect: 1
  • Synthetic Lethality: 2
  • Synthetic Rescue: 3

Resources
Expression Summary
histogram
Resources
Length (a.a.) 182
Molecular Weight (Da) 20,744
Isoelectric Point (pI) 4.6
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrVIII:412907 to 413455 | ORF Map | GBrowse
SGD ORF map
Genetic position: 107 cM
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..549 412907..413455 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000001200
References cited on this page View Complete Literature Guide for REC104
1) Malone RE, et al.  (1991) Isolation of mutants defective in early steps of meiotic recombination in the yeast Saccharomyces cerevisiae. Genetics 128(1):79-88
2) Galbraith AM and Malone RE  (1992) Characterization of REC104, a gene required for early meiotic recombination in the yeast Saccharomyces cerevisiae. Dev Genet 13(6):392-402
3) Jiao K, et al.  (2003) Support for a meiotic recombination initiation complex: interactions among Rec102p, Rec104p, and Spo11p. Mol Cell Biol 23(16):5928-38