Standard Name	REC104
Systematic Name	YHR157W
Feature Type	ORF, Verified
Description	Protein involved in early stages of meiotic recombination; required for meiotic crossing over; forms a complex with Rec102p and Spo11p necessary during the initiation of recombination (1, 2, 3)
Name Description	RECombination 2

Chromosomal Location	ChrVIII:412907 to 413455 | ORF Map | GBrowse
	Genetic position: 107 cM

	View Computational GO annotations for REC104
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	meiotic DNA double-strand break formation (TAS) reciprocal meiotic recombination (IMP)
Cellular Component
Manually curated	condensed nuclear chromosome (IDA)

Classical genetics
null	Rec102p distribution: abnormal
reduction of function	spore germination: decreased sporulation: decreased
Large-scale survey
null	competitive fitness: decreased haploproficient resistance to caffeine: increased resistance to camptothecin: increased resistance to hydroxyurea: increased resistance to cycloheximide: decreased resistance to fluconazole: decreased resistance to bleomycin: increased resistance to benzo[a]pyrene: decreased resistance to amitrole: decreased vacuolar morphology: abnormal vegetative growth: abnormal viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	47 total interaction(s) for 38 unique genes/features.
Physical Interactions	Affinity Capture-Western: 2 Biochemical Activity: 5 Two-hybrid: 8
Genetic Interactions	Dosage Rescue: 4 Negative Genetic: 21 Positive Genetic: 1 Synthetic Growth Defect: 1 Synthetic Lethality: 2 Synthetic Rescue: 3
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrVIII:412907 to 413455 | ORF Map | GBrowse
	Genetic position: 107 cM
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..549 412907..413455 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000001200