Standard Name	RDR1
Systematic Name	YOR380W
Feature Type	ORF, Verified
Description	Transcriptional repressor involved in the control of multidrug resistance; negatively regulates expression of the PDR5 gene; member of the Gal4p family of zinc cluster proteins (1)
Name Description	Repressor of Drug Resistance 1

Chromosomal Location	ChrXV:1051290 to 1052930 | ORF Map | GBrowse

	View Computational GO annotations for RDR1
Molecular Function
Manually curated	sequence-specific DNA binding transcription factor activity (IGI, IMP, ISS)
High-throughput	sequence-specific DNA binding (IDA)
Biological Process
Manually curated	response to xenobiotic stimulus (IMP)
Cellular Component
Manually curated	nucleus (TAS)

Binding motifs	GCGGAWA 2 [Search intergenic regions for GCGGAWA] WGCGGAAV 3 [Search intergenic regions for WGCGGAAV]
Regulatory modules	predicted: stressResponse (457) predicted: cellcycle (227) predicted: stressResponse (457) predicted: cellcycle (227)
Resources	ScerTF | UniProbe | YEASTRACT | YeTFaSCo

Classical genetics
null	resistance to Calcofluor White: decreased respiratory metabolism: decreased viable
Large-scale survey
null	polyphosphate accumulation: abnormal competitive fitness: increased resistance to rhodamine 6-G: normal resistance to cycloheximide: increased resistance to pentachlorophenol: decreased resistance to 4-nitroquinoline N-oxide: normal resistance to ketoconazole: normal resistance to chloramphenicol: normal resistance to oligomycin: normal respiratory growth: absent respiratory growth: decreased starvation resistance: decreased vacuolar morphology: abnormal viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	19 total interaction(s) for 19 unique genes/features.
Physical Interactions	Affinity Capture-MS: 1 Biochemical Activity: 1 Two-hybrid: 10
Genetic Interactions	Negative Genetic: 6 Positive Genetic: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | AspGD Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXV:1051290 to 1052930 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1641 1051290..1052930 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000005907