Standard Name	RDH54 1
Systematic Name	YBR073W
Alias	TID1 2
Feature Type	ORF, Verified
Description	DNA-dependent ATPase; stimulates strand exchange by modifying the topology of double-stranded DNA; involved in recombinational repair of DNA double-strand breaks during mitosis and meiosis; proposed to be involved in crossover interference; interacts with Dmc1p; stimulates Dmc1p and Rad51p (1, 2, 3, 4, 5)
Name Description	RaD54 Homolog 1

Chromosomal Location	ChrII:383112 to 385988 | ORF Map | GBrowse

	View Computational GO annotations for RDH54
Molecular Function
Manually curated	DNA translocase activity (IDA) DNA-dependent ATPase activity (IDA)
Biological Process
Manually curated	DNA geometric change (IDA) heteroduplex formation (IDA) meiotic sister chromatid segregation (IMP) reciprocal meiotic recombination (IGI, IMP)
Cellular Component
Manually curated	nucleus (IC)

Classical genetics
null	chromosome/plasmid maintenance: abnormal colony sectoring: increased
Large-scale survey
null	competitive fitness: decreased dessication resistance: decreased gamma ray resistance: decreased haploproficient lifespan: increased resistance to bleomycin: decreased resistance to methyl methanesulfonate: increased resistance to fluconazole: decreased resistance to cycloheximide: decreased resistance to amitrole: decreased resistance to tunicamycin: decreased resistance to caffeine: decreased sporulation: abnormal toxin resistance: increased viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	101 total interaction(s) for 73 unique genes/features.
Physical Interactions	Affinity Capture-MS: 4 Affinity Capture-RNA: 1 Affinity Capture-Western: 1 Co-localization: 2 Reconstituted Complex: 3 Two-hybrid: 1
Genetic Interactions	Dosage Growth Defect: 1 Dosage Lethality: 1 Dosage Rescue: 1 Negative Genetic: 50 Phenotypic Enhancement: 5 Phenotypic Suppression: 8 Positive Genetic: 7 Synthetic Growth Defect: 9 Synthetic Lethality: 1 Synthetic Rescue: 6
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | AspGD Homologs | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrII:383112 to 385988 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 2011-02-03
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..2877 383112..385988 2011-02-03 2011-02-03
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000000277