RBG2/YGR173W Summary Help

Standard Name RBG2 1
Systematic Name YGR173W
Alias GIR1
Feature Type ORF, Verified
Description Protein with a role in translation; forms a complex with Gir2p; has similarity to mammalian developmentally regulated GTP-binding protein (2, 3)
Name Description RiBosome interacting Gtpase 4
Chromosomal Location
ChrVII:843854 to 844960 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All RBG2 GO evidence and references
  View Computational GO annotations for RBG2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Regulators 3 genes
Resources
Large-scale survey
null
Resources
40 total interaction(s) for 28 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 13
  • Affinity Capture-RNA: 2
  • Affinity Capture-Western: 7
  • Co-fractionation: 1
  • PCA: 2
  • Reconstituted Complex: 1
  • Two-hybrid: 2

Genetic Interactions
  • Negative Genetic: 3
  • Phenotypic Enhancement: 1
  • Positive Genetic: 4
  • Synthetic Growth Defect: 4

Resources
Expression Summary
histogram
Resources
Length (a.a.) 368
Molecular Weight (Da) 41,006
Isoelectric Point (pI) 8.85
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrVII:843854 to 844960 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1107 843854..844960 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000003405
References cited on this page View Complete Literature Guide for RBG2
1) Datta K, et al.  (2005) The yeast GTPase Mtg2p is required for mitochondrial translation and partially suppresses an rRNA methyltransferase mutant, mrm2. Mol Biol Cell 16(2):954-63
2) Li B and Trueb B  (2000) DRG represents a family of two closely related GTP-binding proteins. Biochim Biophys Acta 1491(1-3):196-204
3) Daugeron MC, et al.  (2011) The highly conserved eukaryotic DRG factors are required for efficient translation in a manner redundant with the putative RNA helicase Slh1. Nucleic Acids Res 39(6):2221-33
4) Wout PK, et al.  (2009) Saccharomyces cerevisiae Rbg1 protein and its binding partner Gir2 interact on Polyribosomes with Gcn1. Eukaryot Cell 8(7):1061-71